ZFIN ID: ZDB-GENE-040426-2096
Gene Name: RNA 2',3'-cyclic phosphate and 5'-OH ligase
Gene Symbol: rtcb    Nomenclature History

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Previous Name: zgc:76871

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have RNA ligase (ATP) activity. Predicted to be involved in tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate. Predicted to localize to cytoplasm; nucleus; and tRNA-splicing ligase complex. Orthologous to human RTCB (RNA 2',3'-cyclic phosphate and 5'-OH ligase).
Genome Resources: Alliance (1),  Gene:406376 (1),  Ensembl(GRCz11):ENSDARG00000101047 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu966]
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa33351 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-rtcb N/A 1
    MO2-rtcb N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rtcb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rtcb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process tRNA splicing, via endonucleolytic cleavage and ligation (more)
    Cellular Component cytoplasm (more)
    Molecular Function RNA ligase (ATP) activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript rtcb-201 (1)    Ensembl 541
    mRNA rtcb-202 (1)    Ensembl 1693
    ncRNA ottdart00000061574 (1)    Ensembl 657
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rtcb No data available
    MARKER RELATIONSHIPS
    rtcb Contained in: [BAC] CH73-4I5 (1), CH211-286M4 (1)
    rtcb Encodes: [EST] eu966 (1)
    [cDNA] MGC:76871 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_213103 (1) 1714 nt
    Genomic GenBank:AL845512 (1) 192940 nt
    Select Tool
    Polypeptide UniProtKB:Q6NZS4 (1) 505 aa
    Sequence Information (all 15)
    ORTHOLOGY for rtcb ( Chr: 4 )
    CITATIONS (24)