ZFIN ID: ZDB-GENE-040426-2085
Gene Name: p21 protein (Cdc42/Rac)-activated kinase 5
Gene Symbol: pak5    Nomenclature History

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Previous Names: pak5 (1), pak6 (1), pak7, zgc:76890

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in apoptotic process; cytoskeleton organization; and protein phosphorylation. Is expressed in central nervous system and spinal cord. Orthologous to human PAK5 (p21 (RAC1) activated kinase 5).
Genome Resources: Alliance (1),  Gene:405898 (1),  Ensembl(GRCz11):ENSDARG00000030154 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:76890]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la028291Tg Transgenic Insertion Unknown Unknown DNA
sa23829 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pak5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pak5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process apoptotic process (more)
    Molecular Function ATP binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pak7-201 (1)    Ensembl 4186
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pak5 No data available
    MARKER RELATIONSHIPS
    pak5 Contained in: [Fosmid] CH1073-169H18 (1)
    pak5 Encodes: [cDNA] MGC:76890 (1), MGC:175034 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212962 (1) 3160 nt
    Genomic GenBank:CU655875 (1) 31815 nt
    Select Tool
    Polypeptide UniProtKB:B5DE30 (1) 711 aa
    Sequence Information (all 22)
    ORTHOLOGY for pak5 ( Chr: 20 )
    CITATIONS (25)