ZFIN ID: ZDB-GENE-040426-2017
Gene Name: hexokinase 2
Gene Symbol: hk2    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: DrHXK2 (1), fi09d05 (1), fi17h06 (1), wu:fi09d05 (1), wu:fi17h06 (1), wu:fi31b04, zgc:55926

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have fructokinase activity; glucokinase activity; and mannokinase activity. Predicted to be involved in cellular glucose homeostasis; glucose 6-phosphate metabolic process; and glycolytic process. Predicted to localize to cytosol and mitochondrion. Is expressed in several structures, including alar plate midbrain region; digestive system; hatching gland; musculature system; and nervous system. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human HK2 (hexokinase 2).
Genome Resources: Alliance (1),  Gene:406339 (1),  Ensembl(GRCz11):ENSDARG00000101482 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa33551 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40376 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hk2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hk2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process carbohydrate metabolic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hk2 No data available
    MARKER RELATIONSHIPS
    hk2 Contained in: [BAC] DKEYP-106C11 (1)
    hk2 Encodes: [EST] fi09d05, fi17h06, fi31b04 (1)
    [cDNA] MGC:55926 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_213066 (1) 3213 nt
    Genomic RefSeq:NW_018394570 (1) Blast at MegaBLAST
    Polypeptide UniProtKB:B8JKC9 (1) 919 aa
    Sequence Information (all 25)
    ORTHOLOGY for hk2 ( Chr: 5 )
    CITATIONS (36)