Gene

chia.2

ID
ZDB-GENE-040426-2014
Name
chitinase, acidic.2
Symbol
chia.2 Nomenclature History
Previous Names
  • chia2 (1)
  • wu:fb61c11
  • zgc:55941
  • zgc:77889
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have chitin binding activity and chitinase activity. Predicted to be involved in chitin catabolic process. Predicted to localize to extracellular region. Is expressed in gut and liver. Human ortholog(s) of this gene implicated in asthma and schizophrenia. Orthologous to several human genes including CHIT1 (chitinase 1); CHIA (chitinase acidic); and OVGP1 (oviductal glycoprotein 1).
Genome Resources
Note
None
Expression
All Expression Data
11 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With chia.2 Human Ortholog
No data available
Associated With chia.2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR001579 Glycosyl hydrolases family 18 (GH18) active site
Domain IPR001223 Glycoside hydrolase family 18, catalytic domain
Domain IPR002557 Chitin binding domain
Domain IPR011583 Chitinase II
Homologous_superfamily IPR017853 Glycoside hydrolase superfamily
Homologous_superfamily IPR029070 Chitinase insertion domain superfamily
Homologous_superfamily IPR036508 Chitin binding domain superfamily
Domain Details Per Protein
Protein Length Chitinase II Chitinase insertion domain superfamily Chitin binding domain Chitin binding domain superfamily Glycoside hydrolase family 18, catalytic domain Glycoside hydrolase superfamily Glycosyl hydrolases family 18 (GH18) active site
UniProtKB:Q803B7 470
UniProtKB:Q6P006 470
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations