ZFIN ID: ZDB-GENE-040426-2005
Gene Name: cofactor required for Sp1 transcriptional activation, subunit 7
Gene Symbol: crsp7    Nomenclature History

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Previous Names: wu:fe06c07, wu:fi75a09, zgc:55993

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have transcription coregulator activity. Predicted to be involved in positive regulation of gene expression and regulation of transcription by RNA polymerase II. Predicted to localize to the core mediator complex and mediator complex. Orthologous to human MED26 (mediator complex subunit 26).
Genome Resources: Alliance (1),  Gene:406332 (1),  Ensembl(GRCz11):ENSDARG00000105102 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55993]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17859 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH crsp7 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH crsp7 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription by RNA polymerase II (more)
    Cellular Component mediator complex (more)
    Molecular Function transcription coregulator activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR003617 Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type
    Domain IPR017923 Transcription factor IIS, N-terminal
    Domain IPR031416 Mediator complex subunit 26, C-terminal domain
    Domain IPR031417 Mediator complex subunit 26, middle domain
    Homologous_superfamily IPR035441 TFIIS/LEDGF domain superfamily
    Family IPR042376 Mediator of RNA polymerase II transcription subunit 26
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    ncRNA crsp7-001 (1) 2626
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM crsp7 No data available
    MARKER RELATIONSHIPS
    crsp7 Contained in: [BAC] CH73-380A16 (1)
    crsp7 Encodes: [EST] fe06c07, fi75a09
    [cDNA] MGC:55993 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213059 (1) 2413 bp
    Genomic GenBank:CABZ01053416 (1) 19525 bp
    Polypeptide UniProtKB:Q90YL3 (1) 589 aa
    Sequence Information (all 19)
    ORTHOLOGY for crsp7 ( Chr: 2 )
    CITATIONS (20)