Gene

got1

ID
ZDB-GENE-040426-2003
Name
glutamic-oxaloacetic transaminase 1, soluble
Symbol
got1 Nomenclature History
Previous Names
  • wu:fj63b09
  • zgc:55996
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have L-aspartate:2-oxoglutarate aminotransferase activity. Predicted to be involved in aspartate biosynthetic process. Predicted to localize to cytosol. Is expressed in retina. Human ortholog(s) of this gene implicated in amyloidosis; amyotrophic lateral sclerosis; pancreatic ductal adenocarcinoma; and transient cerebral ischemia. Orthologous to human GOT1 (glutamic-oxaloacetic transaminase 1).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With got1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Aspartate aminotransferase, serum level of, QTL1 614419
Associated With got1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site
Domain IPR004839 Aminotransferase, class I/classII
Family IPR000796 Aspartate/other aminotransferase
Homologous_superfamily IPR015421 Pyridoxal phosphate-dependent transferase, major domain
Homologous_superfamily IPR015422 Pyridoxal phosphate-dependent transferase domain 1
Homologous_superfamily IPR015424 Pyridoxal phosphate-dependent transferase
Domain Details Per Protein
Protein Length Aminotransferase, class I/classII Aminotransferases, class-I, pyridoxal-phosphate-binding site Aspartate/other aminotransferase Pyridoxal phosphate-dependent transferase Pyridoxal phosphate-dependent transferase domain 1 Pyridoxal phosphate-dependent transferase, major domain
UniProtKB:Q7ZUW8 410
UniProtKB:F1QMC6 176
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations