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ZIRC
ZFIN ID: ZDB-GENE-040426-1945
Gene Name: acyl-CoA dehydrogenase medium chain
Gene Symbol: acadm    Nomenclature History

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Previous Names: MCAD (1), fb53e01 (1), wu:fb53e01 (1), zgc:111905, zgc:56101 (1), zgc:76911 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have medium-chain-acyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation and medium-chain fatty acid catabolic process. Predicted to localize to the mitochondrion. Human ortholog(s) of this gene implicated in medium chain acyl-CoA dehydrogenase deficiency. Is expressed in female organism. Orthologous to human ACADM (acyl-CoA dehydrogenase medium chain).
Genome Resources: Alliance (1),  Gene:406283 (1),  Ensembl(GRCz11):ENSDARG00000038900 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56101]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6011 Point Mutation Unknown Splice Site ENU
sa6844 Point Mutation Unknown Premature Stop ENU
sa9731 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38335 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH acadm HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    medium chain acyl-CoA dehydrogenase deficiency Alliance Acyl-CoA dehydrogenase, medium chain, deficiency of 201450
    DISEASE ASSOCIATED WITH acadm VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process fatty acid beta-oxidation (more)
    Cellular Component mitochondrion (more)
    Molecular Function acyl-CoA dehydrogenase activity (more)
    GO Terms (all 9)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA acadm-201 (1)    Ensembl 1662
    acadm-204 (1)    Ensembl 759
    ncRNA acadm-003 (1)    Ensembl 485
    acadm-004 (1)    Ensembl 656
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM acadm No data available
    MARKER RELATIONSHIPS
    acadm Contained in: [BAC] CH211-106K21 (1) (order this), DKEY-15H14 (1) (order this)
    acadm Encodes: [EST] fb53e01
    [STS] unp1693
    [cDNA] MGC:56101 (1) (order this), MGC:76911 (order this), MGC:111905 (1) (order this), MGC:174795 (1) (order this), MGC:192886 (1) (order this)
    acadm Has Artifact: [cDNA] MGC:165432 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213010 (1) 1659 bp
    Genomic GenBank:BX569796 (1) 109947 bp
    Select Tool
    Polypeptide UniProtKB:A2CG95 (1) 426 aa
    Sequence Clusters UniGene:132310 (1)
    Sequence Information (all 37)
    ORTHOLOGY for acadm ( Chr: 2 )
    CITATIONS (37)