ZFIN ID: ZDB-GENE-040426-1922
Gene Name: eukaryotic translation initiation factor 3, subunit I
Gene Symbol: eif3i    Nomenclature History

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Previous Names: eif3s2, hm:zehn0464, wu:fb62b08, zgc:56211 (1), zgc:77823 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have translation initiation factor activity. Involved in liver development and sprouting angiogenesis. Predicted to localize to the eukaryotic translation initiation factor 3 complex. Is expressed in several structures, including digestive system; endothelial cell; nervous system; otic vesicle; and pectoral fin. Orthologous to human EIF3I (eukaryotic translation initiation factor 3 subunit I).
Genome Resources: Alliance (1),  Gene:406263 (1),  Ensembl(GRCz11):ENSDARG00000017445 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010697Tg Transgenic Insertion Exon 2 Premature Stop DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18588 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • DISEASE ASSOCIATED WITH eif3i HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH eif3i VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process liver development (more)
    Cellular Component eukaryotic translation initiation factor 3 complex (more)
    Molecular Function translation initiation factor activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Repeat IPR001680 WD40 repeat
    Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
    Domain IPR017986 WD40-repeat-containing domain
    Conserved_site IPR019775 WD40 repeat, conserved site
    Family IPR027525 Eukaryotic translation initiation factor 3 subunit I
    Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA eif3i-201 (1)    Ensembl 1305
    ncRNA eif3i-002 (1)    Ensembl 729
    eif3i-003 (1)    Ensembl 1334
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM eif3i No data available
    MARKER RELATIONSHIPS
    eif3i Contained in: [BAC] CH73-130A3 (1)
    eif3i Encodes: [EST] fb62b08 (1), fq38d09 (1) (order this), zehn0464 (1)
    [cDNA] MGC:56211 (1), MGC:77823
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212990 (1) 1322 bp
    Genomic GenBank:CU633192 (1) 93120 bp
    Select Tool
    Polypeptide UniProtKB:Q7ZV55 (1) 325 aa
    Sequence Information (all 19)
    ORTHOLOGY for eif3i ( Chr: 19 )
    CITATIONS (35)