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ZIRC
ZFIN ID: ZDB-GENE-040426-1909
Gene Name: tubulin polymerization-promoting protein family member 3
Gene Symbol: tppp3    Nomenclature History

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Previous Name: zgc:77934

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have tubulin binding activity. Predicted to be involved in microtubule bundle formation; microtubule polymerization; and positive regulation of protein polymerization. Predicted to colocalize with the microtubule. Is expressed in Kupffer's vesicle; central nervous system; forerunner cell group; neural tube; and pronephric duct. Orthologous to human TPPP3 (tubulin polymerization promoting protein family member 3).
Genome Resources: Alliance (1),  Gene:393825 (1),  Ensembl(GRCz11):ENSDARG00000030463 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2004 [IMAGE:7141624]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa40948 Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tppp3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tppp3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process microtubule bundle formation (more)
    Cellular Component COLOCALIZES_WITH   microtubule (more)
    Molecular Function tubulin binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR008907 (1)
  • InterPro:IPR011992 (1)
  • InterPro:IPR030795 (1)
  • Pfam:PF05517 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tppp3-201 (1)    Ensembl 1479
    tppp3-202 (1)    Ensembl 412
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tppp3 No data available
    MARKER RELATIONSHIPS
    tppp3 Contained in: [BAC] DKEY-189N10 (1) (order this)
    tppp3 Encodes: [EST] IMAGE:7141624 (1) (order this)
    [cDNA] MGC:77934 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_201335 (1) 1383 bp
    Genomic GenBank:CR381641 (1) 168455 bp
    Select Tool
    Polypeptide UniProtKB:E7FG48 (1) 177 aa
    Sequence Clusters UniGene:23293 (1)
    Sequence Information (all 15)
    ORTHOLOGY for tppp3 ( Chr: 7 )
    CITATIONS (19)