header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-040426-1900
Gene Name: SPO11 initiator of meiotic double stranded breaks
Gene Symbol: spo11    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: zgc:77876 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have DNA binding activity and endodeoxyribonuclease activity, producing 3'-phosphomonoesters. Predicted to be involved in meiotic DNA double-strand break formation; meiotic DNA double-strand break processing; and reciprocal meiotic recombination. Predicted to localize to the chromosome. Orthologous to human SPO11 (SPO11 initiator of meiotic double stranded breaks).
Genome Resources: Alliance (1),  Gene:402982 (1),  Ensembl(GRCz11):ENSDARG00000013837 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:77876]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
uc73 Small Deletion Exon 2 Frameshift, Premature Stop TALEN
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
TALEN1-spo11 1
DISEASE ASSOCIATED WITH spo11 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH spo11 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process chromosome organization involved in meiotic cell cycle (more)
Cellular Component chromosome (more)
Molecular Function ATP binding (more)
GO Terms (all 12)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA spo11-201 (1)    Ensembl 1682
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM spo11 No data available
MARKER RELATIONSHIPS
spo11 Contained in: [BAC] CH211-152J3 (1) (order this)
spo11 Encodes: [cDNA] MGC:77876 (1) (order this), MGC:192913 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_205682 (1) 1588 bp
Genomic GenBank:CR339064 (1) 98209 bp
Select Tool
Polypeptide UniProtKB:F1QVE0 (1) 383 aa
Sequence Clusters UniGene:87390 (1)
Sequence Information (all 14)
ORTHOLOGY for spo11 ( Chr: 23 )
CITATIONS (18)