Gene
spo11
- ID
- ZDB-GENE-040426-1900
- Name
- SPO11 initiator of meiotic double stranded breaks
- Symbol
- spo11 Nomenclature History
- Previous Names
-
- zgc:77876 (1)
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity and endodeoxyribonuclease activity, producing 3'-phosphomonoesters. Involved in chromosome organization involved in meiotic cell cycle. Predicted to localize to nuclear chromosome. Orthologous to human SPO11 (SPO11 initiator of meiotic double stranded breaks).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77876 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR013049 | Spo11/DNA topoisomerase VI, subunit A, N-terminal |
| Domain | IPR034136 | Topoisomerase 6 subunit A/Spo11, TOPRIM domain |
| Family | IPR002815 | Spo11/DNA topoisomerase VI subunit A |
| Family | IPR013048 | Meiotic recombination, Spo11 |
| Homologous_superfamily | IPR036078 | Spo11/DNA topoisomerase VI subunit A superfamily |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Meiotic recombination, Spo11 | Spo11/DNA topoisomerase VI subunit A | Spo11/DNA topoisomerase VI, subunit A, N-terminal | Spo11/DNA topoisomerase VI subunit A superfamily | Topoisomerase 6 subunit A/Spo11, TOPRIM domain | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6P0S6
|
383 |
Interactions and Pathways
No data available
Plasmids
No data available