ZFIN ID: ZDB-GENE-040426-1860
Gene Name: transcription elongation factor A (SII), 3
Gene Symbol: tcea3    Nomenclature History

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Previous Name: zgc:77732 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have translation elongation factor activity and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated; transcription, DNA-templated; and translational elongation. Predicted to localize to the nucleus. Is expressed in adaxial cell; musculature system; neuromast; and somite. Orthologous to human TCEA3 (transcription elongation factor A3).
Genome Resources: Alliance (1),  Gene:402983 (1),  Ensembl(GRCz11):ENSDARG00000004724 (2)
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (9 images) from Thisse et al., 2004 [MGC:77732]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012939Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22897 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42773 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tcea3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tcea3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001222 Zinc finger, TFIIS-type
    Domain IPR003617 Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type
    Domain IPR003618 Transcription elongation factor S-II, central domain
    Family IPR006289 Transcription elongation factor, TFIIS
    Domain IPR017923 Transcription factor IIS, N-terminal
    Family IPR035100 Transcription elongation factor, IIS-type
    Homologous_superfamily IPR035441 TFIIS/LEDGF domain superfamily
    Homologous_superfamily IPR036575 Transcription elongation factor S-II, central domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tcea3-201 (1)    Ensembl 1842
    tcea3-202 (1)    Ensembl 1055
    tcea3-203 (1)    Ensembl 697
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tcea3 No data available
    MARKER RELATIONSHIPS
    tcea3 Contained in: [BAC] CH211-199C22 (1)
    [Fosmid] CH1073-429E15 (1)
    tcea3 Encodes: [cDNA] MGC:77732 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_205683 (1) 1892 bp
    Genomic GenBank:CR855299 (1) 116933 bp
    Select Tool
    Polypeptide UniProtKB:Q6P0U5 (1) 409 aa
    Sequence Information (all 54)
    ORTHOLOGY for tcea3 ( Chr: 16 )
    CITATIONS (25)