ZFIN ID: ZDB-GENE-040426-1848
Gene Name: glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
Gene Symbol: gne
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: zgc:77657 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits UDP-N-acetylglucosamine 2-epimerase activity; involved in chordate embryonic development, locomotion, and muscle fiber development; orthologous to human GNE (glucosamine  ...
GENE EXPRESSION
All Expression Data: Fig. 1 from Daya et al., 2014
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hg17 Point Mutation Intron 11 Splicing Variant, Frameshift, Premature Stop ENU
hg18 Point Mutation Exon 12 Missense ENU
hg22 Small Deletion Unknown Frameshift, Premature Stop CRISPR
hg23 Small Deletion Exon 5 Frameshift, Premature Stop CRISPR
la013561Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa4834 Point Mutation Unknown Premature Stop ENU
    sa19447 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31197 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko269b Indel Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 4 figures from Daya et al., 2014
    Observed in:
    DISEASE ASSOCIATED WITH gne HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    inclusion body myositis Nonaka myopathy 605820
    sialuria Sialuria 269921
    DISEASE ASSOCIATED WITH gne VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chordate embryonic development (more)
    Cellular Component cellular_component (more)
    Molecular Function UDP-N-acetylglucosamine 2-epimerase activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000600 (1)
  • InterPro:IPR003331 (1)
  • InterPro:IPR020004 (1)
  • InterPro:IPR029767 (1)
  • Pfam:PF00480 (1)
  • Pfam:PF02350 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA gne-003 (1) 857
    mRNA gne-201 (1) 3669
    gne-203 (1) 801
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM gne
    MARKER RELATIONSHIPS
    gneContained in: [BAC] CH73-340C23 (1) (order this), CH211-109N19 (1) (order this), CH211-288H2 (1) (order this)
    gneEncodes: [cDNA] MGC:77657 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200883 (1) 3632bp
    Genomic GenBank:CT033816 (1) 166556bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4II12 (1) 748aa
    Sequence Clusters UniGene:80099 (1)
    Sequence Information (all 16)
    OTHER gne GENE PAGES
  • Alliance (1)
  • Gene:393857 (1)
  • VEGA:OTTDARG00000033050 (1)
  • Ensembl(GRCz11):ENSDARG00000099771 (1)
  • ORTHOLOGY for gne (Chr: 1)
    CITATIONS (24)