ZFIN ID: ZDB-GENE-040426-1847
Gene Name: glyoxylate reductase/hydroxypyruvate reductase b
Gene Symbol: grhprb
Sequence Ontology ID : SO:0000704

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Previous Names: fb80f04, wu:fb80f04, zgc:77636

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(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have glyoxylate reductase (NADP) activity, hydroxypyruvate reductase activity, and protein homodimerization activity; predicted to be involved in oxidation-reduction process; predicted  ...
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 7 figures (11 images) from Thisse et al., 2004 [MGC:77636]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17209 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19472 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko384a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH grhprb HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    primary hyperoxaluria Hyperoxaluria, primary, type II 260000
    DISEASE ASSOCIATED WITH grhprb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component cytosol (more)
    Molecular Function NAD binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR006139 (1)
  • InterPro:IPR006140 (1)
  • InterPro:IPR029752 (1)
  • InterPro:IPR029753 (1)
  • InterPro:IPR036291 (1)
  • PROSITE:PS00065 (1)
  • PROSITE:PS00671 (1)
  • Pfam:PF00389 (1)
  • Pfam:PF02826 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA grhprb-001 (1) 2454
    grhprb-002 (1) 1276
    grhprb-003 (1) 733
    ncRNA grhprb-004 (1) 426
    grhprb-006 (1) 1068
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM grhprb No data available
    MARKER RELATIONSHIPS
    grhprbContained in: [BAC] DKEY-82J4 (1) (order this)
    grhprbContains: [STS] chunp30555
    grhprbEncodes: [EST] fb80f04
    [cDNA] MGC:77636 (1) (order this)
    grhprbHas Artifact: [EST] fb65e02
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_205685 (1) 1307bp
    Genomic GenBank:CR387920 (1) 70948bp
    Select Tool
    Polypeptide UniProtKB:F1QYH7 (1) 361aa
    Sequence Clusters UniGene:105154 (1)
    Sequence Information (all 19)
    OTHER grhprb GENE PAGES
  • Alliance (1)
  • Gene:402985 (1)
  • VEGA:OTTDARG00000021662 (1)
  • ORTHOLOGY for grhprb (Chr: 1)
    CITATIONS (19)