Gene

scp2a

ID
ZDB-GENE-040426-1846
Name
sterol carrier protein 2a
Symbol
scp2a Nomenclature History
Previous Names
  • scp2
  • zgc:77634
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have lipid binding activity; propanoyl-CoA C-acyltransferase activity; and propionyl-CoA C2-trimethyltridecanoyltransferase activity. Predicted to be involved in positive regulation of intracellular cholesterol transport. Predicted to localize to mitochondrion and peroxisome. Is expressed in intestinal bulb; lens; liver; and solid lens vesicle. Orthologous to human SCP2 (sterol carrier protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With scp2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Leukoencephalopathy with dystonia and motor neuropathy 613724
Associated With scp2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR020615 Thiolase, acyl-enzyme intermediate active site
Conserved_site IPR020613 Thiolase, conserved site
Domain IPR003033 SCP2 sterol-binding domain
Domain IPR020616 Thiolase, N-terminal
Domain IPR020617 Thiolase, C-terminal
Homologous_superfamily IPR016039 Thiolase-like
Homologous_superfamily IPR036527 SCP2 sterol-binding domain superfamily
Domain Details Per Protein
Protein Length SCP2 sterol-binding domain SCP2 sterol-binding domain superfamily Thiolase, acyl-enzyme intermediate active site Thiolase, conserved site Thiolase, C-terminal Thiolase-like Thiolase, N-terminal
UniProtKB:Q6P4V5 538
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations