Gene
plxnd1
- ID
- ZDB-GENE-040426-1828
- Name
- plexin D1
- Symbol
- plxnd1 Nomenclature History
- Previous Names
-
- obd
- out of bounds
- zgc:77379
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable semaphorin receptor activity. Acts upstream of or within with a negative effect on sprouting angiogenesis. Acts upstream of or within angioblast cell migration; branching involved in blood vessel morphogenesis; and embryonic eye morphogenesis. Predicted to be located in plasma membrane. Is expressed in lateral mesoderm; pharyngeal arch 3-7; vascular cord; and vasculature. Orthologous to human PLXND1 (plexin D1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 22 figures from 10 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001627 | Sema domain |
| Domain | IPR002909 | IPT domain |
| Domain | IPR013548 | Plexin, cytoplasmic RasGAP domain |
| Domain | IPR016201 | PSI domain |
| Domain | IPR041019 | Plexin, TIG domain 1 |
| Domain | IPR042719 | Plexin-D1, sema domain |
| Family | IPR031148 | Plexin family |
| Homologous_superfamily | IPR008936 | Rho GTPase activation protein |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR014756 | Immunoglobulin E-set |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036352 | Sema domain superfamily |
| Repeat | IPR002165 | Plexin repeat |
Domain Details Per Protein
| Protein | Length | Immunoglobulin E-set | Immunoglobulin-like fold | IPT domain | Plexin, cytoplasmic RasGAP domain | Plexin-D1, sema domain | Plexin family | Plexin repeat | Plexin, TIG domain 1 | PSI domain | Rho GTPase activation protein | Sema domain | Sema domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7FGF3
|
752 | |||||||||||||
|
UniProtKB:Q6DSU3
|
1880 | |||||||||||||
|
UniProtKB:Q6NZU7
|
637 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available