Gene

plxnd1

ID
ZDB-GENE-040426-1828
Name
plexin D1
Symbol
plxnd1 Nomenclature History
Previous Names
  • obd
  • out of bounds
  • zgc:77379
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have semaphorin receptor activity. Involved in blood vessel morphogenesis and embryonic eye morphogenesis. Predicted to localize to integral component of membrane and plasma membrane. Is expressed in lateral mesoderm; pharyngeal arch 3-7; vascular cord; and vasculature. Orthologous to human PLXND1 (plexin D1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
26 figures from 11 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With plxnd1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Congenital heart defects, multiple types, 9 620294
Associated With plxnd1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001627 Sema domain
Domain IPR002909 IPT domain
Domain IPR013548 Plexin, cytoplasmic RasGAP domain
Domain IPR016201 PSI domain
Domain IPR041019 Plexin, TIG domain 1
Domain IPR042719 Plexin-D1, sema domain
Domain IPR046800 Plexin, cytoplasmic RhoGTPase-binding domain
Family IPR031148 Plexin family
Homologous_superfamily IPR008936 Rho GTPase activation protein
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR014756 Immunoglobulin E-set
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036352 Sema domain superfamily
Repeat IPR002165 Plexin repeat
Domain Details Per Protein
Protein Length Immunoglobulin E-set Immunoglobulin-like fold IPT domain Plexin, cytoplasmic RasGAP domain Plexin, cytoplasmic RhoGTPase-binding domain Plexin-D1, sema domain Plexin family Plexin repeat Plexin, TIG domain 1 PSI domain Rho GTPase activation protein Sema domain Sema domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:E7FGF3 752
UniProtKB:Q6DSU3 1880
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations