ZFIN ID: ZDB-GENE-040426-1821
Gene Name: neuroplastin b
Gene Symbol: nptnb    Nomenclature History

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Previous Names: nptn, zgc:77326

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have cell-cell adhesion mediator activity. Predicted to be involved in axon guidance; dendrite self-avoidance; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to localize to axon and plasma membrane. Is expressed in basal plate midbrain region and nervous system. Orthologous to human NPTN (neuroplastin).
Genome Resources: Alliance (1),  Gene:403006 (1),  Ensembl(GRCz11):ENSDARG00000043864 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa162 Point Mutation Unknown Premature Stop ENU
sa1762 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12048 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31019 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43023 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nptnb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nptnb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axon guidance (more)
    Cellular Component integral component of membrane (more)
    Molecular Function cell-cell adhesion mediator activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nptnb-202 (1)    Ensembl 1686
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nptnb No data available
    MARKER RELATIONSHIPS
    nptnb Contained in: [Fosmid] CH1073-75F15 (1)
    nptnb Encodes: [EST] cssl:d0159 (1), cssl:d0299 (1)
    [cDNA] MGC:77326 (1), MGC:175052 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_205705 (1) 2611 nt
    Genomic GenBank:CU469514 (1) 34943 nt
    Select Tool
    Polypeptide UniProtKB:A4JYK5 (1) 403 aa
    Sequence Information (all 24)
    ORTHOLOGY for nptnb ( Chr: 18 )
    CITATIONS (22)