Gene

pnp6

ID
ZDB-GENE-040426-1800
Name
purine nucleoside phosphorylase 6
Symbol
pnp6 Nomenclature History
Previous Names
  • zgc:77182 (1)
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to have purine-nucleoside phosphorylase activity. Predicted to be involved in nucleoside metabolic process. Predicted to localize to cytoplasm. Is expressed in pronephros; sensory system; and solid lens vesicle. Human ortholog(s) of this gene implicated in purine nucleoside phosphorylase deficiency and purine-pyrimidine metabolic disorder. Orthologous to human PNP (purine nucleoside phosphorylase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pnp6 Human Ortholog
No data available
Associated With pnp6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018099 Purine phosphorylase, family 2, conserved site
Domain IPR000845 Nucleoside phosphorylase domain
Family IPR011268 Purine nucleoside phosphorylase
Family IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific
Homologous_superfamily IPR035994 Nucleoside phosphorylase superfamily
Domain Details Per Protein
Protein Length Nucleoside phosphorylase domain Nucleoside phosphorylase superfamily Purine nucleoside phosphorylase Purine nucleoside phosphorylase I, inosine/guanosine-specific Purine phosphorylase, family 2, conserved site
UniProtKB:Q1LWJ2 128
UniProtKB:Q1LWJ1 286
UniProtKB:Q6P0H3 286
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations