ZFIN ID: ZDB-GENE-040426-1800
Gene Name: purine nucleoside phosphorylase 6
Gene Symbol: pnp6    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: zgc:77182 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have purine-nucleoside phosphorylase activity. Predicted to be involved in nucleoside metabolic process. Predicted to localize to cytoplasm. Is expressed in pronephros; sensory system; and solid lens vesicle. Human ortholog(s) of this gene implicated in purine nucleoside phosphorylase deficiency and purine-pyrimidine metabolic disorder. Orthologous to human PNP (purine nucleoside phosphorylase).
Genome Resources: Alliance (1),  Gene:402953 (1),  Ensembl(GRCz11):ENSDARG00000040942 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa36643 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pnp6 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pnp6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process nucleobase-containing compound metabolic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pnp6-201 (1)    Ensembl 1829
    pnp6-202 (1)    Ensembl 491
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pnp6 No data available
    MARKER RELATIONSHIPS
    pnp6 Contained in: [BAC] CH211-245P7 (1)
    pnp6 Encodes: [cDNA] MGC:77182 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_205655 (1) 1801 nt
    Genomic GenBank:BX548070 (1) 173372 nt
    Select Tool
    Polypeptide UniProtKB:Q1LWJ1 (1) 286 aa
    Sequence Information (all 13)
    ORTHOLOGY for pnp6 ( Chr: 18 )
    CITATIONS (23)