Gene

txn2

ID
ZDB-GENE-040426-1795
Name
thioredoxin 2
Symbol
txn2 Nomenclature History
Previous Names
  • zgc:77127
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Is predicted to enable protein-disulfide reductase activity. Acts upstream of or within cell redox homeostasis and glycerol ether metabolic process. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 29. Orthologous to human TXN2 (thioredoxin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With txn2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
combined oxidative phosphorylation deficiency 29 Alliance ?Combined oxidative phosphorylation deficiency 29 616811
Associated With txn2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017937 Thioredoxin, conserved site
Domain IPR013766 Thioredoxin domain
Family IPR005746 Thioredoxin
Homologous_superfamily IPR036249 Thioredoxin-like superfamily
Domain Details Per Protein
Protein Length Thioredoxin Thioredoxin, conserved site Thioredoxin domain Thioredoxin-like superfamily
UniProtKB:Q6P131 166
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations