ZFIN ID: ZDB-GENE-040426-1795
Gene Name: thioredoxin 2
Gene Symbol: txn2    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: zgc:77127

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have protein disulfide oxidoreductase activity. Predicted to be involved in cell redox homeostasis and glycerol ether metabolic process. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 29. Orthologous to human TXN2 (thioredoxin 2).
Genome Resources: Alliance (1),  Gene:402938 (1),  Ensembl(GRCz11):ENSDARG00000034777 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:77127]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la015282Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH txn2 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    combined oxidative phosphorylation deficiency 29 Alliance ?Combined oxidative phosphorylation deficiency 29 616811
    DISEASE ASSOCIATED WITH txn2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell redox homeostasis (more)
    Molecular Function protein disulfide oxidoreductase activity (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA txn2-201 (1)    Ensembl 1236
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM txn2 No data available
    MARKER RELATIONSHIPS
    txn2 Contained in: [BAC] CH211-150D5 (1)
    txn2 Encodes: [cDNA] MGC:77127 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_205641 (1) 1220 nt
    Genomic GenBank:AL772329 (1) 163559 nt
    Select Tool
    Polypeptide UniProtKB:Q6P131 (1) 166 aa
    Sequence Information (all 8)
    ORTHOLOGY for txn2 ( Chr: 3 )
    CITATIONS (23)