Gene

uqcrc1

ID
ZDB-GENE-040426-1792
Name
ubiquinol-cytochrome c reductase core protein 1
Symbol
uqcrc1 Nomenclature History
Previous Names
  • zgc:73404 (1)
  • zgc:85750
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have catalytic activity and metal ion binding activity. Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to localize to mitochondrial inner membrane. Is expressed in several structures, including cerebellum; epidermis; gut; inner ear; and liver and biliary system. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human UQCRC1 (ubiquinol-cytochrome c reductase core protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With uqcrc1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Parkinsonism with polyneuropathy 619279
Associated With uqcrc1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR007863 Peptidase M16, C-terminal
Domain IPR011765 Peptidase M16, N-terminal
Homologous_superfamily IPR011249 Metalloenzyme, LuxS/M16 peptidase-like
Domain Details Per Protein
Protein Length Metalloenzyme, LuxS/M16 peptidase-like Peptidase M16, C-terminal Peptidase M16, N-terminal
UniProtKB:F1QUE3 503
UniProtKB:Q6NSN3 474
UniProtKB:Q6PBH6 474
UniProtKB:A0A2R8Q5U6 503
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations