ZFIN ID: ZDB-GENE-040426-1792
Gene Name: ubiquinol-cytochrome c reductase core protein 1
Gene Symbol: uqcrc1    Nomenclature History

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Previous Names: zgc:73404 (1), zgc:85750

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have catalytic activity and metal ion binding activity. Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to localize to mitochondrial inner membrane. Is expressed in several structures, including cerebellum; epidermis; gut; inner ear; and liver and biliary system. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human UQCRC1 (ubiquinol-cytochrome c reductase core protein 1).
Genome Resources: Alliance (1),  Gene:393793 (1),  Ensembl(GRCz11):ENSDARG00000052304 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1488 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-uqcrc1
    1
    CRISPR2-uqcrc1
    1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH uqcrc1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH uqcrc1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mitochondrial electron transport, ubiquinol to cytochrome c (more)
    Cellular Component mitochondrial inner membrane (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA uqcrc1-201 (1)    Ensembl 1897
    ncRNA uqcrc1-202 (1)    Ensembl 565
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM uqcrc1 No data available
    MARKER RELATIONSHIPS
    uqcrc1 Contained in: [BAC] DKEY-162P13 (1) (order this)
    uqcrc1 Encodes: [EST] fq37a01 (1) (order this)
    [cDNA] MGC:73404 (1), MGC:85750 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200820 (1) 1715 nt
    Genomic GenBank:BX928750 (1) 178487 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8Q5U6 (1) 503 aa
    Sequence Information (all 15)
    ORTHOLOGY for uqcrc1 ( Chr: 6 )
    CITATIONS (29)