ZFIN ID: ZDB-GENE-040426-1774
Gene Name: clusterin
Gene Symbol: clu    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: zgc:73352

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have misfolded protein binding activity. Involved in regulation of neuron death. Predicted to localize to extracellular space and nucleus. Is expressed in several structures, including digestive system; male organism; nervous system; notochord; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in artery disease (multiple); breast cancer; diabetic retinopathy; exfoliation syndrome; and muscular disease (multiple). Orthologous to human CLU (clusterin).
Genome Resources: Alliance (1),  Gene:393775 (1),  Ensembl(GRCz11):ENSDARG00000010434 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-clu N/A 1
DISEASE ASSOCIATED WITH clu HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH clu VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process regulation of neuron death (more)
Cellular Component chromaffin granule (more)
Molecular Function misfolded protein binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA clu-201 (1)    Ensembl 1772
clu-202 (1)    Ensembl 770
clu-203 (1)    Ensembl 731
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM clu No data available
MARKER RELATIONSHIPS
clu Contained in: [BAC] DKEY-217M5 (1) (order this)
clu Encodes: [EST] fq20d12 (1) (order this)
[cDNA] MGC:73352 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_200802 (1) 1688 nt
Genomic GenBank:AL845306 (1) 186675 nt
Select Tool
Polypeptide UniProtKB:A0A0B5JQ03 (1) 449 aa
Sequence Information (all 22)
ORTHOLOGY for clu ( Chr: 20 )
CITATIONS (28)