Gene
cap2
- ID
- ZDB-GENE-040426-1758
- Name
- cyclase associated actin cytoskeleton regulatory protein 2
- Symbol
- cap2 Nomenclature History
- Previous Names
-
- zgc:113089
- zgc:73317
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to have actin binding activity and adenylate cyclase binding activity. Predicted to be involved in several processes, including actin polymerization or depolymerization; cell morphogenesis; and regulation of adenylate cyclase activity. Predicted to localize to cortical actin cytoskeleton. Is expressed in central nervous system; heart; male organism; muscle; and neural tube. Orthologous to human CAP2 (cyclase associated actin cytoskeleton regulatory protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Effendi et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Effendi et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Cardiomyopathy, dilated, 2I | 620462 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018106 | CAP, conserved site, N-terminal |
| Conserved_site | IPR028417 | CAP, conserved site, C-terminal |
| Domain | IPR006599 | CARP motif |
| Domain | IPR013912 | Adenylate cyclase-associated CAP, C-terminal |
| Domain | IPR013992 | Adenylate cyclase-associated CAP, N-terminal |
| Domain | IPR017901 | C-CAP/cofactor C-like domain |
| Family | IPR001837 | Adenylate cyclase-associated CAP |
| Homologous_superfamily | IPR016098 | Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal |
| Homologous_superfamily | IPR036222 | Adenylate cyclase-associated CAP, N-terminal domain superfamily |
| Homologous_superfamily | IPR036223 | Adenylate cyclase-associated CAP, C-terminal superfamily |
Domain Details Per Protein
| Protein | Length | Adenylate cyclase-associated CAP | Adenylate cyclase-associated CAP, C-terminal | Adenylate cyclase-associated CAP, C-terminal superfamily | Adenylate cyclase-associated CAP, N-terminal | Adenylate cyclase-associated CAP, N-terminal domain superfamily | CAP, conserved site, C-terminal | CAP, conserved site, N-terminal | CARP motif | C-CAP/cofactor C-like domain | Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IXA9
|
468 | ||||||||||
|
UniProtKB:Q5BJ21
|
461 |
Interactions and Pathways
No data available
Plasmids
No data available