ZFIN ID: ZDB-GENE-040426-1758
Gene Name: cyclase associated actin cytoskeleton regulatory protein 2
Gene Symbol: cap2    Nomenclature History

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Previous Names: zgc:113089, zgc:73317

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have actin binding activity and adenylate cyclase binding activity. Predicted to be involved in several processes, including actin polymerization or depolymerization; establishment or maintenance of cell polarity; and regulation of adenylate cyclase activity. Predicted to localize to cortical actin cytoskeleton. Is expressed in central nervous system; heart; male organism; muscle; and neural tube. Orthologous to human CAP2 (cyclase associated actin cytoskeleton regulatory protein 2).
Genome Resources: Alliance (1),  Gene:393809 (1),  Ensembl(GRCz11):ENSDARG00000104478 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32263 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-cap2 N/A 1
    MO2-cap2 N/A 1
    PHENOTYPE
    Data: Fig. 2 from Effendi et al., 2013
    Observed in:
    DISEASE ASSOCIATED WITH cap2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cap2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell morphogenesis (more)
    Cellular Component cortical actin cytoskeleton (more)
    Molecular Function actin binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cap2-202 (1)    Ensembl 3214
    ncRNA cap2-002 (1)    Ensembl 615
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cap2 No data available
    MARKER RELATIONSHIPS
    cap2 Contained in: [Fosmid] CH1073-175O15 (1), CH1073-228H2 (1), CH1073-243K12 (1)
    cap2 Encodes: [cDNA] MGC:73317 (1), MGC:113089 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200836 (1) 3122 nt
    Genomic GenBank:CU856142 (1) 31900 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IXA9 (1) 468 aa
    Sequence Information (all 20)
    ORTHOLOGY for cap2 ( Chr: 19 )
    CITATIONS (16)