ZFIN ID: ZDB-GENE-040426-1729
Gene Name: fibroblast growth factor 1a
Gene Symbol: fgf1a    Nomenclature History

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Previous Names: fgf1, zgc:73249

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have S100 protein binding activity; heparin binding activity; and signaling receptor binding activity. Involved in hemopoiesis. Predicted to localize to cytosol and extracellular space. Is expressed in blastodisc; endoderm; mesoderm; retina; and somite. Human ortholog(s) of this gene implicated in brain ischemia; cleft lip; myocardial infarction; schizophrenia; and urinary bladder cancer. Orthologous to human FGF1 (fibroblast growth factor 1).
Genome Resources: Alliance (1),  Gene:393733 (1),  Ensembl(GRCz11):ENSDARG00000017542 (1)
GENE EXPRESSION
All Expression Data: 8 figures from 6 publications
Directly Submitted Expression Data: 3 figures (5 images) from Thisse et al., 2004 [MGC:73249]
Wild-type Stages, Structures: Blastula:512-cell (2.75h-3.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
vu526 Small Deletion Exon 1 Frameshift, Premature Stop TALEN
vu527 Small Deletion Exon 1 Frameshift, Premature Stop TALEN
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-fgf1a N/A 1
MO2-fgf1a N/A 1
TALEN1-fgf1a 1
DISEASE ASSOCIATED WITH fgf1a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH fgf1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process hemopoiesis (more)
Cellular Component cytosol (more)
Molecular Function fibroblast growth factor receptor binding (more)
GO Terms (all 24)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA fgf1a-201 (1)    Ensembl 1805
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM fgf1a No data available
MARKER RELATIONSHIPS
fgf1a Contained in: [BAC] CH211-119P14 (1)
fgf1a Encodes: [cDNA] MGC:73249 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_200760 (1) 1729 nt
Genomic GenBank:BX470157 (1) 201228 nt Blast at MegaBLAST
Polypeptide UniProtKB:A0A0R4I9A1 (1) 147 aa
Sequence Information (all 12)
ORTHOLOGY for fgf1a ( Chr: 14 )
CITATIONS (35)