Gene

uqcc2

ID
ZDB-GENE-040426-1726
Name
ubiquinol-cytochrome c reductase complex assembly factor 2
Symbol
uqcc2 Nomenclature History
Previous Names
  • zgc:73238
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to be involved in several processes, including mitochondrial respiratory chain complex III assembly; positive regulation of cellular protein metabolic process; and regulation of insulin secretion. Predicted to localize to mitochondrial inner membrane; mitochondrial intermembrane space; and mitochondrial nucleoid. Is expressed in intestinal bulb; intestinal bulb primordium; liver; and pectoral fin musculature. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 7. Orthologous to human UQCC2 (ubiquinol-cytochrome c reductase complex assembly factor 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With uqcc2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
mitochondrial complex III deficiency nuclear type 7 Alliance Mitochondrial complex III deficiency, nuclear type 7 615824
Associated With uqcc2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR037698 Ubiquinol-cytochrome-c reductase complex assembly factor 2
Family IPR046827 Complex III assembly factor UQCC2/CBP6
Domain Details Per Protein
Protein Length Complex III assembly factor UQCC2/CBP6 Ubiquinol-cytochrome-c reductase complex assembly factor 2
UniProtKB:Q6PBU7 129
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA uqcc2-201 (1) Havana 711 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations