ZFIN ID: ZDB-GENE-040426-1713
Gene Name: NADH:ubiquinone oxidoreductase core subunit V2
Gene Symbol: ndufv2    Nomenclature History

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Previous Name: zgc:73198

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have 2 iron, 2 sulfur cluster binding activity; metal ion binding activity; and oxidoreductase activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to localize to mitochondrial respiratory chain complex I. Is expressed in several structures, including alar plate midbrain region; digestive system; optic tectum; optic vesicle; and retina. Human ortholog(s) of this gene implicated in Parkinson's disease and mitochondrial complex I deficiency. Orthologous to human NDUFV2 (NADH:ubiquinone oxidoreductase core subunit V2).
Genome Resources: Alliance (1),  Gene:393720 (1),  Ensembl(GRCz11):ENSDARG00000013044 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (5 images) from Thisse et al., 2004 [MGC:73198]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH ndufv2 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Mitochondrial complex I deficiency, nuclear type 7 618229
DISEASE ASSOCIATED WITH ndufv2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component mitochondrial respiratory chain complex I (more)
Molecular Function 2 iron, 2 sulfur cluster binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ndufv2 No data available
MARKER RELATIONSHIPS
ndufv2 Encodes: [cDNA] MGC:73198 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_200747 (1)
Genomic GenBank:FO907121 (1) 37779 nt
Select Tool
Polypeptide UniProtKB:Q6PBX8 (1) 244 aa
Sequence Information (all 10)
ORTHOLOGY for ndufv2 ( Chr: 2 )
CITATIONS (20)