Gene

gnb5b

ID
ZDB-GENE-040426-1712
Name
guanine nucleotide binding protein (G protein), beta 5b
Symbol
gnb5b Nomenclature History
Previous Names
  • gnb5
  • zgc:73196
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to contribute to GTPase activator activity. Predicted to be involved in G protein-coupled receptor signaling pathway; dopamine receptor signaling pathway; and positive regulation of GTPase activity. Predicted to localize to cytoplasm and heterotrimeric G-protein complex. Is expressed in cardiovascular system; cranial ganglion; neurons; and visual system. Orthologous to human GNB5 (G protein subunit beta 5).
Genome Resources
Note
None
Expression
All Expression Data
13 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gnb5b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Intellectual developmental disorder with cardiac arrhythmia 617173
Language delay and ADHD/cognitive impairment with or without cardiac arrhythmia 617182
Associated With gnb5b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019775 WD40 repeat, conserved site
Domain IPR001632 G-protein, beta subunit
Domain IPR017986 WD40-repeat-containing domain
Family IPR016346 Guanine nucleotide-binding protein, beta subunit
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Domain Details Per Protein
Protein Length G-protein, beta subunit Guanine nucleotide-binding protein, beta subunit WD40 repeat WD40 repeat, conserved site WD40-repeat-containing domain WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:Q6PBY0 395
UniProtKB:F1R9V4 212
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations