ZFIN ID: ZDB-GENE-040426-1711
Gene Name: amphiphysin
Gene Symbol: amph    Nomenclature History

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Previous Names: wu:fq25h04, zgc:73193 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have phospholipid binding activity. Predicted to be involved in synaptic vesicle endocytosis. Localizes to cytoplasm. Is expressed in several structures, including fin; gonad; heart; nervous system; and neural tube. Orthologous to human AMPH (amphiphysin).
Genome Resources: Alliance (1),  Gene:393804 (1),  Ensembl(GRCz11):ENSDARG00000007663 (2)
GENE EXPRESSION
All Expression Data: 15 figures from 3 publications
Directly Submitted Expression Data: 12 figures (32 images) from Rauch et al., 2003 [fq25h04]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1386 Point Mutation Unknown Splice Site ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH amph HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH amph VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process synaptic vesicle endocytosis (more)
Cellular Component cytoplasm (more)
Molecular Function phospholipid binding (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA amph-201 (1)    Ensembl 3424
ncRNA amph-002 (1)    Ensembl 494
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM amph No data available
MARKER RELATIONSHIPS
amph Contained in: [BAC] DKEYP-13D12 (1)
amph Encodes: [EST] fq25h04 (1) (order this)
[cDNA] MGC:73193 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_200831 (1) 3420 nt
Genomic GenBank:BX323064 (1) 170480 nt
Select Tool
Polypeptide UniProtKB:A0A0S3NTN0 (1) 784 aa
Sequence Information (all 52)
ORTHOLOGY for amph ( Chr: 2 )
CITATIONS (24)