Gene
rgs9b
- ID
- ZDB-GENE-040426-1708
- Name
- regulator of G protein signaling 9b
- Symbol
- rgs9b Nomenclature History
- Previous Names
-
- zgc:73189 (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activator activity. Predicted to be involved in G protein-coupled dopamine receptor signaling pathway. Predicted to act upstream of or within several processes, including G protein-coupled receptor signaling pathway; regulation of signal transduction; and visual perception. Predicted to be located in membrane. Predicted to be active in cytoplasm; neuron projection; and plasma membrane. Is expressed in eye and telencephalon. Human ortholog(s) of this gene implicated in bradyopsia 1. Orthologous to human RGS9 (regulator of G protein signaling 9).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| bradyopsia 1 | Alliance | Prolonged electroretinal response suppression 1 | 608415 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000591 | DEP domain |
| Domain | IPR015898 | G-protein gamma-like domain |
| Domain | IPR016137 | RGS domain |
| Domain | IPR040759 | Regulator of G-protein signalling, DHEX domain |
| Domain | IPR047077 | Regulator of G protein signaling 9, RGS domain |
| Family | IPR047016 | Regulator of G protein signaling 6/7/9/11 |
| Homologous_superfamily | IPR036284 | G-protein gamma-like domain superfamily |
| Homologous_superfamily | IPR036305 | RGS domain superfamily |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
| Homologous_superfamily | IPR044926 | RGS, subdomain 2 |
| Homologous_superfamily | IPR047017 | Regulator of G-protein signalling 6/7/9/11, DHEX domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | DEP domain | G-protein gamma-like domain | G-protein gamma-like domain superfamily | Regulator of G protein signaling 6/7/9/11 | Regulator of G protein signaling 9, RGS domain | Regulator of G-protein signalling 6/7/9/11, DHEX domain superfamily | Regulator of G-protein signalling, DHEX domain | RGS domain | RGS domain superfamily | RGS, subdomain 2 | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9Q8K8 | InterPro | 441 | ||||||||||||
| UniProtKB:A0A8M9PWJ6 | InterPro | 661 | ||||||||||||
| UniProtKB:Q6ZM84 | InterPro | 661 |
Interactions and Pathways
No data available
Plasmids
No data available