ZFIN ID: ZDB-GENE-040426-1702
Gene Name: exosome component 4
Gene Symbol: exosc4
Sequence Ontology ID : SO:0000704

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Previous Names: exosome complex exonuclease RRP41 (1), zgc:73175

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(Including Attributions)
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (15 images) from Thisse et al., 2004 [MGC:73175]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
  alar plate midbrain region, immature eye, midbrain, neural plate (all 13) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi340bTg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in: eye, gut, head, liver (all 5) expand
    DISEASE ASSOCIATED WITH exosc4 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process U4 snRNA 3'-end processing (more)
    Cellular Component cytoplasmic exosome (RNase complex) (more)
    Molecular Function exonuclease activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001247
  • InterPro:IPR015847
  • InterPro:IPR020568
  • InterPro:IPR027408
  • Pfam:PF01138
  • Pfam:PF03725
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA exosc4-001 (1) 782
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM exosc4 No data available
    MARKER RELATIONSHIPS
    exosc4Contained in: [Fosmid] ZFOS-2284C12 (1)
    exosc4Encodes: [cDNA] MGC:73175 (1) (order this), MGC:174480 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200739 (1) 1647bp
    Genomic GenBank:FO704880 (1) 37227bp
    Select Tool
    Polypeptide UniProtKB:Q6PBZ8 245aa
    Sequence Clusters UniGene:107456 (1)
    Sequence Information (all 18)
    OTHER exosc4 GENE PAGES
  • Gene:393712 (1)
  • VEGA:OTTDARG00000040916 (1)
  • Ensembl(GRCz10):ENSDARG00000103432 (1)
  • ORTHOLOGY for exosc4 (Chr: 2)
    CITATIONS (19)