Gene

rims2a

ID
ZDB-GENE-040426-1656
Name
regulating synaptic membrane exocytosis 2a
Symbol
rims2a Nomenclature History
Previous Names
  • rims2
  • zgc:73064
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have Rab GTPase binding activity and ion channel binding activity. Predicted to be involved in calcium ion-regulated exocytosis of neurotransmitter; modulation of chemical synaptic transmission; and regulation of membrane potential. Predicted to localize to cytoskeleton of presynaptic active zone and presynaptic membrane. Is expressed in nervous system and pancreatic system. Orthologous to human RIMS2 (regulating synaptic membrane exocytosis 2).
Genome Resources
Note
None
Expression
All Expression Data
6 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rims2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Cone-rod synaptic disorder syndrome, congenital nonprogressive 618970
Associated With rims2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000008 C2 domain
Family IPR030631 Regulating synaptic membrane exocytosis protein 2
Family IPR039032 Rim-like
Homologous_superfamily IPR035892 C2 domain superfamily
Domain Details Per Protein
Protein Length C2 domain C2 domain superfamily Regulating synaptic membrane exocytosis protein 2 Rim-like
UniProtKB:Q6PC83 286
UniProtKB:A0A0R4IUL9 286
UniProtKB:A0A0R4IBD3 337
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations