Gene

tuba8l2

ID
ZDB-GENE-040426-1646
Name
tubulin, alpha 8 like 2
Symbol
tuba8l2 Nomenclature History
Previous Names
  • zgc:73046 (1)
  • zgc:77601 (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to localize to cytoplasm and microtubule. Is expressed in gill. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 22. Orthologous to human TUBA4A (tubulin alpha 4a).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tuba8l2 Human Ortholog
No data available
Associated With tuba8l2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017975 Tubulin, conserved site
Domain IPR003008 Tubulin/FtsZ, GTPase domain
Domain IPR018316 Tubulin/FtsZ, 2-layer sandwich domain
Family IPR000217 Tubulin
Family IPR002452 Alpha tubulin
Homologous_superfamily IPR008280 Tubulin/FtsZ, C-terminal
Homologous_superfamily IPR023123 Tubulin, C-terminal
Homologous_superfamily IPR036525 Tubulin/FtsZ, GTPase domain superfamily
Homologous_superfamily IPR037103 Tubulin/FtsZ, C-terminal domain superfamily
Domain Details Per Protein
Protein Length Alpha tubulin Tubulin Tubulin, conserved site Tubulin, C-terminal Tubulin/FtsZ, 2-layer sandwich domain Tubulin/FtsZ, C-terminal Tubulin/FtsZ, C-terminal domain superfamily Tubulin/FtsZ, GTPase domain Tubulin/FtsZ, GTPase domain superfamily
UniProtKB:Q6TNP4 449
UniProtKB:Q6PC95 449
UniProtKB:Q6P5N0 449
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations