ZFIN ID: ZDB-GENE-040426-1640
Gene Name: deltex E3 ubiquitin ligase 3
Gene Symbol: dtx3    Nomenclature History

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Previous Names: fi25g12, wu:fi25g12, zgc:66440

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have metal ion binding activity. Predicted to be involved in Notch signaling pathway and protein ubiquitination. Orthologous to human DTX3 (deltex E3 ubiquitin ligase 3).
Genome Resources: Alliance (1),  Gene:393500 (1),  Ensembl(GRCz11):ENSDARG00000025766 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66440]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa37726 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dtx3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dtx3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process Notch signaling pathway (more)
    Cellular Component nucleoplasm (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001841 Zinc finger, RING-type
    Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
    Conserved_site IPR017907 Zinc finger, RING-type, conserved site
    Domain IPR039396 Deltex, C-terminal
    Family IPR039398 Deltex family
    Homologous_superfamily IPR039399 Deltex, C-terminal domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA zgc:66440-201 (1)    Ensembl 2585
    zgc:66440-202 (1)    Ensembl 2449
    zgc:66440-203 (1)    Ensembl 566
    zgc:66440-204 (1)    Ensembl 807
    zgc:66440-205 (1)    Ensembl 614
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dtx3 No data available
    MARKER RELATIONSHIPS
    dtx3 Contained in: [BAC] DKEY-157G16 (1) (order this)
    dtx3 Encodes: [EST] fi25g12
    [cDNA] MGC:66440 (1), MGC:109734 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200528 (1) 2469 bp
    Genomic GenBank:CR354433 (1) 205769 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1QUJ1 (1) 384 aa
    Sequence Information (all 33)
    ORTHOLOGY for dtx3 ( Chr: 23 )
    CITATIONS (16)