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ZIRC
ZFIN ID: ZDB-GENE-040426-1620
Gene Name: ring finger protein 180
Gene Symbol: rnf180    Nomenclature History

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Previous Name: zgc:66368 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in norepinephrine metabolic process; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and serotonin metabolic process. Predicted to localize to the intrinsic component of endoplasmic reticulum membrane. Orthologous to human RNF180 (ring finger protein 180).
Genome Resources: Alliance (1),  Gene:793295 (1),  Ensembl(GRCz11):ENSDARG00000057101 (1)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66368]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa37285 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rnf180 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rnf180 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein polyubiquitination (more)
    Cellular Component integral component of membrane (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 10)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rnf180-001 (1) 1987
    ncRNA rnf180-002 (1)    Ensembl 875
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rnf180 No data available
    MARKER RELATIONSHIPS
    rnf180 Contained in: [BAC] DKEY-246J23 (1) (order this)
    rnf180 Encodes: [cDNA] MGC:66368 (1) (order this), MGC:174819 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001110404 (1) 1977 bp
    Genomic GenBank:BX511186 (1) 138351 bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8RJ75 (1) 458 aa
    Sequence Clusters UniGene:78834 (1)
    Sequence Information (all 15)
    ORTHOLOGY for rnf180 ( Chr: 21 )
    CITATIONS (18)