ZFIN ID: ZDB-GENE-040426-1616
Gene Name: seryl-tRNA synthetase 2, mitochondrial
Gene Symbol: sars2    Nomenclature History

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Previous Name: zgc:66345 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have serine-tRNA ligase activity. Predicted to be involved in seryl-tRNA aminoacylation. Predicted to localize to the cytoplasm. Orthologous to human SARS2 (seryl-tRNA synthetase 2, mitochondrial).
Genome Resources: Alliance (1),  Gene:394154 (1),  Ensembl(GRCz11):ENSDARG00000102736 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66345]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
PHENOTYPE No data available
DISEASE ASSOCIATED WITH sars2 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Hyperuricemia, pulmonary hypertension, renal failure, and alkalosis 613845
DISEASE ASSOCIATED WITH sars2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process seryl-tRNA aminoacylation (more)
Cellular Component mitochondrion (more)
Molecular Function aminoacyl-tRNA ligase activity (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)
Family IPR002317 Serine-tRNA ligase, type1
Domain IPR006195 Aminoacyl-tRNA synthetase, class II
Homologous_superfamily IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm
Domain IPR033729 Serine-tRNA ligase catalytic core domain
Homologous_superfamily IPR042103 Serine-tRNA synthetase, type1, N-terminal domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA sars2-201 (1)    Ensembl 1751
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM sars2 No data available
MARKER RELATIONSHIPS
sars2 Contained in: [BAC] DKEY-260J18 (1) (order this)
sars2 Encodes: [cDNA] MGC:66345 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_201179 (1) 1816 bp
Genomic GenBank:CR388387 (1) 138115 bp
Select Tool
Polypeptide UniProtKB:A3QJX4 (1) 510 aa
Sequence Information (all 15)
ORTHOLOGY for sars2 ( Chr: 15 )
CITATIONS (19)