Gene

ambp

ID
ZDB-GENE-040426-1608
Name
alpha-1-microglobulin/bikunin precursor
Symbol
ambp Nomenclature History
Previous Names
  • ambpl (1)
  • zgc:66321
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to act upstream of or within protein-chromophore linkage. Predicted to be located in extracellular region. Predicted to be active in cell surface and plasma membrane. Is expressed in liver and yolk syncytial layer. Human ortholog(s) of this gene implicated in acute kidney failure and adult respiratory distress syndrome. Orthologous to human AMBP (alpha-1-microglobulin/bikunin precursor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Pickart et al., 2006
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ambp Human Ortholog
No data available
Associated With ambp Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020901 Proteinase inhibitor I2, Kunitz, conserved site
Domain IPR000566 Lipocalin/cytosolic fatty-acid binding domain
Domain IPR002223 Pancreatic trypsin inhibitor Kunitz domain
Family IPR002968 Alpha-1-microglobulin
Family IPR029856 Protein AMBP
Homologous_superfamily IPR012674 Calycin
Homologous_superfamily IPR036880 Pancreatic trypsin inhibitor Kunitz domain superfamily
Domain Details Per Protein
Protein Length Alpha-1-microglobulin Calycin Lipocalin/cytosolic fatty-acid binding domain Pancreatic trypsin inhibitor Kunitz domain Pancreatic trypsin inhibitor Kunitz domain superfamily Protein AMBP Proteinase inhibitor I2, Kunitz, conserved site
UniProtKB:Q7SXH6 216
UniProtKB:A0A2R8PW45 350
UniProtKB:A0A2R8Q9N1 346
UniProtKB:A7E2Q2 346
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations