Gene

klc1a

ID

ZDB-GENE-040426-1599

Name

kinesin light chain 1a

Symbol

klc1a Nomenclature History

Previous Names

zgc:66299 (1)

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to have microtubule motor activity. Predicted to localize to kinesin complex. Human ortholog(s) of this gene implicated in Alzheimer's disease and relapsing-remitting multiple sclerosis. Is expressed in central nervous system; cranial ganglion; neurons; retina; and retinal ganglion cell layer. Orthologous to human KLC1 (kinesin light chain 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:66299 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With klc1a Human Ortholog

No data available

Associated With klc1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR002151	Kinesin light chain
Homologous_superfamily	IPR011990	Tetratricopeptide-like helical domain superfamily
Repeat	IPR015792	Kinesin light chain repeat
Repeat	IPR019734	Tetratricopeptide repeat

Domain Details Per Protein

Protein	Length	Kinesin light chain	Kinesin light chain repeat	Tetratricopeptide-like helical domain superfamily	Tetratricopeptide repeat
UniProtKB:A0A8M2B3J0 InterPro	647
UniProtKB:A0A8M2B2P5 InterPro	557
UniProtKB:A0A8M2B2S3 InterPro	548
UniProtKB:F1QS14 InterPro	605
UniProtKB:Q7SXI2 InterPro	538
UniProtKB:A0A8M3AYZ1 InterPro	638