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ZIRC
ZFIN ID: ZDB-GENE-040426-1584
Gene Name: cytochrome P450, family 2, subfamily K, polypeptide 18
Gene Symbol: cyp2k18    Nomenclature History

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Previous Name: zgc:66268

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in several processes, including exogenous drug catabolic process; organic acid metabolic process; and xenobiotic metabolic process. Predicted to localize to the cytoplasm and intracellular membrane-bounded organelle. Orthologous to human CYP2W1 (cytochrome P450 family 2 subfamily W member 1).
Genome Resources: Alliance (1),  Gene:393484 (1),  Ensembl(GRCz11):ENSDARG00000104593 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66268]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa9457 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa26005 Point Mutation Unknown Premature Stop ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cyp2k18 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cyp2k18 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component cytoplasm (more)
    Molecular Function heme binding (more)
    GO Terms (all 11)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cyp2k18-201 (1)    Ensembl 2335
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cyp2k18
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(-7.3cyp2k18:EGFP) cyp2k18 EGFP Danio rerio 1 1
    MARKER RELATIONSHIPS
    cyp2k18 Contained in: [BAC] CH211-155I15 (1) (order this)
    cyp2k18 Encodes: [cDNA] MGC:66268 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200512 (1) 2353 bp
    Genomic GenBank:AL929078 (1) 171571 bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IBN6 (1) 455 aa
    Sequence Clusters UniGene:104299 (1)
    Sequence Information (all 12)
    ORTHOLOGY for cyp2k18 ( Chr: 3 )
    CITATIONS (20)