ZFIN ID: ZDB-GENE-040426-1583
Gene Name: cathepsin S, ortholog 1
Gene Symbol: ctss1    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: ctssa (1), zgc:66267

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in cellular protein catabolic process. Predicted to localize to the extracellular space and lysosome. Human ortholog(s) of this gene implicated in neuropathy. Orthologous to human CTSS (cathepsin S).
Genome Resources: Alliance (1),  Gene:393398 (1),  Ensembl(GRCz11):ENSDARG00000036940 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66267]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH ctss1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH ctss1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process proteolysis (more)
Cellular Component extracellular space (more)
Molecular Function cysteine-type peptidase activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Active_site IPR000169 Cysteine peptidase, cysteine active site
Active_site IPR025660 Cysteine peptidase, histidine active site
Active_site IPR025661 Cysteine peptidase, asparagine active site
Domain IPR000668 Peptidase C1A, papain C-terminal
Domain IPR013201 Cathepsin propeptide inhibitor domain (I29)
Domain IPR039417 Papain-like cysteine endopeptidase
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA ctss1-201 (1)    Ensembl 1702
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ctss1 No data available
MARKER RELATIONSHIPS
ctss1 Contained in: [BAC] DKEYP-24A7 (1)
ctss1 Encodes: [cDNA] MGC:66267 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_200426 (1) 1664 nt
Genomic GenBank:CR548627 (1) 146348 nt
Select Tool
Polypeptide UniProtKB:Q1L8W8 (1) 328 aa
Sequence Information (all 16)
ORTHOLOGY for ctss1 ( Chr: 19 )
CITATIONS (25)