Gene

guca1e

ID
ZDB-GENE-040426-1577
Name
guanylate cyclase activator 1e
Symbol
guca1e Nomenclature History
Previous Names
  • gcap5 (1)
  • zgc:66243
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Exhibits calcium sensitive guanylate cyclase activator activity; identical protein binding activity; and metal ion binding activity. Predicted to be involved in response to stimulus and visual perception. Predicted to localize to photoreceptor outer segment. Is expressed in eye and retina. Human ortholog(s) of this gene implicated in cone-rod dystrophy 14. Orthologous to human GUCA1A (guanylate cyclase activator 1A).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With guca1e Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cone-rod dystrophy 14 Alliance Cone dystrophy-3 602093
cone-rod dystrophy 14 Alliance Cone-rod dystrophy 14 602093
Associated With guca1e Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR018247 EF-Hand 1, calcium-binding site
Domain IPR002048 EF-hand domain
Family IPR028846 Recoverin family
Family IPR033022 Guanylyl cyclase-activating protein 1
Homologous_superfamily IPR011992 EF-hand domain pair
Domain Details Per Protein
Protein Length EF-Hand 1, calcium-binding site EF-hand domain EF-hand domain pair Guanylyl cyclase-activating protein 1 Recoverin family
UniProtKB:A0A0R4IPX8 198
UniProtKB:A0A0R4IPJ4 132
UniProtKB:Q6PFM5 198
UniProtKB:Q5MAC8 198
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations