header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-040426-1565
Gene Name: acyl-CoA synthetase long chain family member 4a
Gene Symbol: acsl4a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: acsl4, acsl4b, zgc:66186 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have catalytic activity. Involved in dorsal/ventral pattern formation and regulation of signal transduction. Predicted to localize to the integral component of membrane. Human ortholog(s) of this gene implicated in intellectual disability and non-syndromic X-linked intellectual disability. Is expressed in several structures, including digestive system; heart; nervous system; pleuroperitoneal region; and yolk syncytial layer. Orthologous to human ACSL4 (acyl-CoA synthetase long chain family member 4).
Genome Resources: Alliance (1),  Gene:393622 (1),  Ensembl(GRCz11):ENSDARG00000004078 (2)
GENE EXPRESSION
All Expression Data: 9 figures from 3 publications
Directly Submitted Expression Data: 6 figures (9 images) from Thisse et al., 2004 [MGC:66186]
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa35699 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-acsl4a N/A 1
    MO2-acsl4a N/A 1
    MO3-acsl4a N/A 1
    MO4-acsl4a N/A 1
    MO5-acsl4a N/A 1
    DISEASE ASSOCIATED WITH acsl4a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    non-syndromic X-linked intellectual disability Alliance Mental retardation, X-linked 63 300387
    DISEASE ASSOCIATED WITH acsl4a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dorsal/ventral pattern formation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 7)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA acsl4a-201 (1)    Ensembl 3852
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM acsl4a No data available
    MARKER RELATIONSHIPS
    acsl4a Contained in: [BAC] CH73-86C12 (1) (order this), DKEY-18F5 (1) (order this)
    acsl4a Encodes: [cDNA] MGC:66186 (1) (order this), MGC:191744 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200649 (1) 3863 bp
    Genomic GenBank:BX088535 (1) 197465 bp
    Select Tool
    Polypeptide UniProtKB:F1R452 (1) 706 aa
    Sequence Clusters UniGene:78711 (1)
    Sequence Information (all 19)
    ORTHOLOGY for acsl4a ( Chr: 14 )
    CITATIONS (25)