Gene

prpf31

ID
ZDB-GENE-040426-1561
Name
PRP31 pre-mRNA processing factor 31 homolog (yeast)
Symbol
prpf31 Nomenclature History
Previous Names
  • zgc:66177 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have U4atac snRNA binding activity. Involved in mRNA splicing, via spliceosome and retina development in camera-type eye. Predicted to localize to nucleus. Is expressed in retina and retinal neural layer. Used to study retinitis pigmentosa. Human ortholog(s) of this gene implicated in retinitis pigmentosa 11. Orthologous to human PRPF31 (pre-mRNA processing factor 31).
Genome Resources
Note
None
Expression
All Expression Data
6 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prpf31 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
retinitis pigmentosa 11 Alliance Retinitis pigmentosa 11 600138
Associated With prpf31 Via Experimental Models
Human Disease Fish Conditions Citations
retinitis pigmentosa WT + MO1-prpf31 standard conditions (2)
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002687 Nop domain
Domain IPR012976 NOSIC
Domain IPR019175 Prp31 C-terminal
Family IPR027105 U4/U6 small nuclear ribonucleoprotein Prp31
Homologous_superfamily IPR029012 Helix hairpin bin domain superfamily
Homologous_superfamily IPR036070 Nop domain superfamily
Homologous_superfamily IPR042239 Nop, C-terminal domain
Domain Details Per Protein
Protein Length Helix hairpin bin domain superfamily Nop, C-terminal domain Nop domain Nop domain superfamily NOSIC Prp31 C-terminal U4/U6 small nuclear ribonucleoprotein Prp31
UniProtKB:E9QCW6 240
UniProtKB:Q7SXM7 508
UniProtKB:B2GS36 508
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations