Gene
nae1
- ID
- ZDB-GENE-040426-1552
- Name
- nedd8 activating enzyme E1 subunit 1
- Symbol
- nae1 Nomenclature History
- Previous Names
-
- appbp1
- zgc:66148
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have NEDD8 activating enzyme activity. Predicted to be involved in protein neddylation. Predicted to localize to cytoplasm. Orthologous to human NAE1 (NEDD8 activating enzyme E1 subunit 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with dysmorphic facies and ischiopubic hypoplasia | 620210 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | NEDD8-activating enzyme E1 regulatory subunit APP-BP1 | ThiF/MoeB/HesA family | THIF-type NAD/FAD binding fold | Ubiquitin-activating enzyme |
|---|---|---|---|---|---|
|
UniProtKB:Q7SXP2
|
533 |
Interactions and Pathways
No data available
Plasmids
No data available