ZFIN ID: ZDB-GENE-040426-1552
Gene Name: nedd8 activating enzyme E1 subunit 1
Gene Symbol: nae1    Nomenclature History

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Previous Names: appbp1, zgc:66148

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have NEDD8 activating enzyme activity. Predicted to be involved in protein neddylation. Predicted to localize to cytoplasm. Orthologous to human NAE1 (NEDD8 activating enzyme E1 subunit 1).
Genome Resources: Alliance (1),  Gene:573336 (1),  Ensembl(GRCz11):ENSDARG00000011301 (1)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66148]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7138842]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026093Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34155 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40985 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nae1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nae1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein neddylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function NEDD8 activating enzyme activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nae1-201 (1)    Ensembl 1829
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nae1 No data available
    MARKER RELATIONSHIPS
    nae1 Contained in: [BAC] DKEY-71E3 (1) (order this)
    nae1 Encodes: [EST] IMAGE:7138842 (1)
    [cDNA] MGC:66148 (1), MGC:171400 (1), MGC:198186 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200499 (1) 1843 nt
    Genomic GenBank:BX511136 187217 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4ICE9 (1) 548 aa
    Sequence Information (all 21)
    ORTHOLOGY for nae1 ( Chr: 7 )
    CITATIONS (26)