ZFIN ID: ZDB-GENE-040426-1546
Gene Name: heterogeneous nuclear ribonucleoprotein A1a
Gene Symbol: hnrnpa1a    Nomenclature History

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Previous Name: zgc:66127 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have mRNA binding activity. Predicted to be involved in regulation of RNA metabolic process. Predicted to localize to nucleus and ribonucleoprotein complex. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 20; inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 3; and tropical spastic paraparesis. Orthologous to human HNRNPA1 (heterogeneous nuclear ribonucleoprotein A1).
Genome Resources: Alliance (1),  Gene:393467 (1),  Ensembl(GRCz11):ENSDARG00000011020 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66127]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la011960Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la011962Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la011964Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la017743Tg Transgenic Insertion Unknown Unknown DNA
    la017745Tg Transgenic Insertion Unknown Unknown DNA
    la027247Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-hnrnpa1a
    1
    CRISPR2-hnrnpa1a
    1
    MO1-hnrnpa1a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hnrnpa1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    amyotrophic lateral sclerosis type 20 Alliance Amyotrophic lateral sclerosis 20 615426
    inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 3 Alliance ?Inclusion body myopathy with early-onset Paget disease without frontotemporal dementia 3 615424
    DISEASE ASSOCIATED WITH hnrnpa1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Molecular Function nucleic acid binding (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hnrnpa1a No data available
    MARKER RELATIONSHIPS
    hnrnpa1a Encodes: [cDNA] MGC:66127 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200495 (1) 1513 nt
    Genomic GenBank:CABZ01092718 (1) 6000 nt
    Polypeptide UniProtKB:E7FAQ8 (1) 388 aa
    Sequence Information (all 27)
    ORTHOLOGY for hnrnpa1a ( Chr: 11 )
    CITATIONS (28)