ZFIN ID: ZDB-GENE-040426-1539
Gene Name: pyruvate dehydrogenase complex component X
Gene Symbol: pdhx    Nomenclature History

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Previous Names: zgc:66110, zgc:85977 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to contribute to pyruvate dehydrogenase (NAD+) activity. Predicted to localize to mitochondrion and pyruvate dehydrogenase complex. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Orthologous to human PDHX (pyruvate dehydrogenase complex component X).
Genome Resources: Alliance (1),  Gene:393532 (1),  Ensembl(GRCz11):ENSDARG00000051756 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:85977]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa30318 Point Mutation Unknown Splice Site ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH pdhx HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
pyruvate decarboxylase deficiency Alliance Lacticacidemia due to PDX1 deficiency 245349
DISEASE ASSOCIATED WITH pdhx VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Cellular Component mitochondrion (more)
Molecular Function transferase activity (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA pdhx-201 (1)    Ensembl 1822
pdhx-202 (1)    Ensembl 1812
ncRNA pdhx-003 (1)    Ensembl 638
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM pdhx No data available
MARKER RELATIONSHIPS
pdhx Contained in: [Fosmid] CH1073-288B16 (1)
pdhx Encodes: [cDNA] MGC:66110 (1), MGC:85977, MGC:174504 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_200560 (1) 1866 nt
Genomic GenBank:CU633770 (1) 35489 nt
Select Tool
Polypeptide UniProtKB:F1R0J8 (1) 496 aa
Sequence Information (all 22)
ORTHOLOGY for pdhx ( Chr: 25 )
CITATIONS (21)