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General Information
ZIRC
ZFIN ID: ZDB-GENE-040426-1526
Gene Name: cytochrome b-245, alpha polypeptide
Gene Symbol: cyba
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: P22phox (1), zgc:66077 (1)

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(Including Attributions)
Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have superoxide-generating NADPH oxidase activity. Involved in macrophage chemotaxis and neutrophil migration. Predicted to localize to the NADPH oxidase complex. Human ortholog(s) of  ...
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66077]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH cyba HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
autosomal recessive chronic granulomatous disease cytochrome b-negative Chronic granulomatous disease, autosomal, due to deficiency of CYBA 233690
DISEASE ASSOCIATED WITH cyba VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process neutrophil migration (more)
Cellular Component integral component of membrane (more)
Molecular Function heme binding (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR007732 (1)
  • Pfam:PF05038 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA cyba-002 (1) 452
    cyba-003 (1) 711
    cyba-004 (1) 516
    mRNA cyba-201 (1) 1120
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cyba No data available
    MARKER RELATIONSHIPS
    cybaContained in: [BAC] CH211-220F20 (1) (order this)
    cybaEncodes: [cDNA] MGC:66077 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200579 (1) 1115bp
    Genomic GenBank:CR936382 (1) 78500bp
    Select Tool
    Polypeptide UniProtKB:Q6PH62 (1) 185aa
    Sequence Clusters UniGene:83382 (1)
    Sequence Information (all 9)
    ORTHOLOGY for cyba (Chr: 18)
    CITATIONS (35)