Gene
slc22a4
- ID
- ZDB-GENE-040426-1517
- Name
- solute carrier family 22 member 4
- Symbol
- slc22a4 Nomenclature History
- Previous Names
-
- octn1 (1)
- zgc:66036
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have quaternary ammonium group transmembrane transporter activity. Involved in several processes, including detoxification of mercury ion; response to methylmercury; and selenium compound metabolic process. Predicted to localize to integral component of membrane. Is expressed in eye; head; heart; and skeletal muscle. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Orthologous to human SLC22A4 (solute carrier family 22 member 4).
- Genome Resources
- Note
- None
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- No data available
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| rheumatoid arthritis | Alliance | {Rheumatoid arthritis, susceptibility to} | 180300 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Major facilitator, sugar transporter-like | Major facilitator superfamily domain | MFS transporter superfamily | Sugar transporter, conserved site |
|---|---|---|---|---|---|
|
UniProtKB:Q6P695
|
553 | ||||
|
UniProtKB:F1QKX0
|
553 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
slc22a4-201
(1)
|
1766 nt | |
| ncRNA |
slc22a4-002
(1)
|
897 nt | |
| ncRNA |
slc22a4-003
(1)
|
824 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Gene Tree
- Ensembl