Gene

slc22a4

ID
ZDB-GENE-040426-1517
Name
solute carrier family 22 member 4
Symbol
slc22a4 Nomenclature History
Previous Names
  • octn1 (1)
  • zgc:66036
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have quaternary ammonium group transmembrane transporter activity. Involved in several processes, including detoxification of mercury ion; response to methylmercury; and selenium compound metabolic process. Predicted to localize to integral component of membrane. Is expressed in eye; head; heart; and skeletal muscle. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Orthologous to human SLC22A4 (solute carrier family 22 member 4).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc22a4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
rheumatoid arthritis Alliance {Rheumatoid arthritis, susceptibility to} 180300
Associated With slc22a4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR005829 Sugar transporter, conserved site
Domain IPR020846 Major facilitator superfamily domain
Family IPR005828 Major facilitator, sugar transporter-like
Homologous_superfamily IPR036259 MFS transporter superfamily
Domain Details Per Protein
Protein Length Major facilitator, sugar transporter-like Major facilitator superfamily domain MFS transporter superfamily Sugar transporter, conserved site
UniProtKB:Q6P695 553
UniProtKB:F1QKX0 553
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations