Gene

trip13

ID

ZDB-GENE-040426-1488

Name

thyroid hormone receptor interactor 13

Symbol

trip13 Nomenclature History

Previous Names

im:6901078
zgc:65952 (1)

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to enable ATP binding activity; ATP hydrolysis activity; and identical protein binding activity. Predicted to be involved in several processes, including double-strand break repair; meiosis I; and meiotic recombination checkpoint signaling. Predicted to act upstream of or within cell differentiation and meiotic cell cycle. Predicted to be active in chromosome and nucleus. Human ortholog(s) of this gene implicated in mosaic variegated aneuploidy syndrome 3. Orthologous to human TRIP13 (thyroid hormone receptor interactor 13).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6901078 (1 image)
bc056713 (7 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With trip13 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
mosaic variegated aneuploidy syndrome 3	Alliance	Mosaic variegated aneuploidy syndrome 3	617598
		Oocyte/zygote/embryo maturation arrest 9	619011

Associated With trip13 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR003960	ATPase, AAA-type, conserved site
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR003959	ATPase, AAA-type, core
Family	IPR044539	Pachytene checkpoint protein 2-like
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

Domain Details Per Protein

Protein	Additional Resources	Length	AAA+ ATPase domain	ATPase, AAA-type, conserved site	ATPase, AAA-type, core	Pachytene checkpoint protein 2-like	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:Q6PH52	InterPro	424
UniProtKB:A0A8M2BHH9	InterPro	424

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	trip13-201 (1) Ensembl	Ensembl	1,718 nt	Select Tool ZFIN BLAST
mRNA	trip13-202 (1) Ensembl	Ensembl	511 nt	Select Tool ZFIN BLAST
mRNA	trip13-203 (1) Ensembl	Ensembl	751 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations