Gene

cdkal1

ID
ZDB-GENE-040426-1443
Name
CDK5 regulatory subunit associated protein 1-like 1
Symbol
cdkal1 Nomenclature History
Previous Names
  • zgc:65864
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have N6-threonylcarbomyladenosine methylthiotransferase activity. Involved in pancreas regeneration and type B pancreatic cell development. Predicted to localize to endoplasmic reticulum. Human ortholog(s) of this gene implicated in diabetes mellitus; gestational diabetes; and type 2 diabetes mellitus. Orthologous to human CDKAL1 (CDK5 regulatory subunit associated protein 1 like 1).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from O'Hare et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdkal1 Human Ortholog
No data available
Associated With cdkal1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002792 TRAM domain
Domain IPR007197 Radical SAM
Homologous_superfamily IPR023404 Radical SAM, alpha/beta horseshoe
Domain Details Per Protein
Protein Length Radical SAM Radical SAM, alpha/beta horseshoe TRAM domain
UniProtKB:A0A0G2KLR5 250
UniProtKB:Q6PG34 547
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations