Gene

bmp5

ID
ZDB-GENE-040426-1413
Name
bone morphogenetic protein 5
Symbol
bmp5 Nomenclature History
Previous Names
  • bmp5l (1)
  • hm:zehl0669 (1)
  • zehl0669
  • zgc:64230 (1)
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have BMP receptor binding activity and cytokine activity. Involved in neural crest cell development; positive regulation of ERK1 and ERK2 cascade; and positive regulation of pathway-restricted SMAD protein phosphorylation. Predicted to localize to extracellular space. Is expressed in several structures, including neural crest; optic vesicle; periderm; pharyngeal arch; and sensory system. Orthologous to human BMP5 (bone morphogenetic protein 5).
Genome Resources
Note
None
Expression
All Expression Data
10 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bmp5 Human Ortholog
No data available
Associated With bmp5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017948 Transforming growth factor beta, conserved site
Domain IPR001111 TGF-beta, propeptide
Domain IPR001839 Transforming growth factor-beta, C-terminal
Family IPR015615 Transforming growth factor-beta-related
Homologous_superfamily IPR029034 Cystine-knot cytokine
Domain Details Per Protein
Protein Length Cystine-knot cytokine TGF-beta, propeptide Transforming growth factor beta, conserved site Transforming growth factor-beta, C-terminal Transforming growth factor-beta-related
UniProtKB:Q7T288 446
UniProtKB:A0A0R4ILD5 446
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations