ZFIN ID: ZDB-GENE-040426-1404
Gene Name: WD repeat domain, phosphoinositide interacting 1
Gene Symbol: wipi1    Nomenclature History

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Previous Name: zgc:64205 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have phosphatidylinositol-3,5-bisphosphate binding activity and phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in several processes, including autophagy of mitochondrion; autophagy of nucleus; and protein localization to phagophore assembly site. Predicted to localize to cytosol; extrinsic component of membrane; and phagophore assembly site membrane. Is expressed in central nervous system; notochord; and periderm. Orthologous to human WIPI1 (WD repeat domain, phosphoinositide interacting 1).
Genome Resources: Alliance (1),  Gene:393362 (1),  Ensembl(GRCz11):ENSDARG00000040657 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (4 images) from Thisse et al., 2004 [MGC:64205]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa40111 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-wipi1 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH wipi1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH wipi1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process autophagy (more)
    Cellular Component cytosol (more)
    Molecular Function phosphatidylinositol-3-phosphate binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA wipi1-201 (1)    Ensembl 2213
    ncRNA wipi1-002 (1)    Ensembl 415
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM wipi1 No data available
    MARKER RELATIONSHIPS
    wipi1 Contained in: [BAC] CH211-117C2 (1), CH211-234H8 (1)
    wipi1 Encodes: [cDNA] MGC:64205 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200391 (1) 2187 nt
    Genomic GenBank:BX897685 (1) 179286 nt
    Select Tool
    Polypeptide UniProtKB:B0S7L1 (1) 453 aa
    Sequence Information (all 13)
    ORTHOLOGY for wipi1 ( Chr: 3 )
    CITATIONS (23)