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Gene

stn1

ID
ZDB-GENE-040426-1390
Name
STN1 subunit of CST complex
Symbol
stn1 Nomenclature History
Previous Names
  • obfc1
  • zgc:64174 (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable single-stranded telomeric DNA binding activity. Acts upstream of or within vasculature development. Predicted to be located in chromosome, telomeric region. Predicted to be part of CST complex. Predicted to be active in nucleus. Used to study telangiectasis. Orthologous to human STN1 (STN1 subunit of CST complex).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Simon et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With stn1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Cerebroretinal microangiopathy with calcifications and cysts 2 617341
Associated With stn1 Via Experimental Models
Human Disease Fish Conditions Citations
telangiectasis AB + MO1-stn1 standard conditions Simon et al., 2016
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type
Domain IPR015253 Stn1, C-terminal
Family IPR014647 CST complex subunit Stn1
Family IPR040260 Replication factor A protein-like
Homologous_superfamily IPR012340 Nucleic acid-binding, OB-fold
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Homologous_superfamily IPR042082 CST complex subunit Stn1, N-terminal domain superfamily
Domain Details Per Protein
Protein Length CST complex subunit Stn1 CST complex subunit Stn1, N-terminal domain superfamily Nucleic acid-binding, OB-fold OB-fold nucleic acid binding domain, AA-tRNA synthetase-type Replication factor A protein-like Stn1, C-terminal Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:B8JKF4 368
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations